WEBINAR

Mastering Membrane Proteins in days with mimetic screening

illustration of 4 different types of membrane protein within nanodisc. Enzyes, GPCRs, Transporters and Ion channels
Introduction:

Join Cube Biotech and Nuclera to discover a rapid, scalable workflow for expressing and stabilizing complex membrane proteins. Learn how Cube Biotech’s membrane mimetics combined with Nuclera’s eProtein Discovery™ system enable stable, functional, assay-ready membrane proteins in just 48 hours. This webinar highlights case studies on key drug targets, demonstrating how optimized membrane protein production accelerates structural biology, drug screening, and therapeutic development.

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Webinar Topics:

  • Best practices for screening and selecting membrane mimetics to enhance protein stability, function and yield
  • Cell-free workflows for membrane protein production from DNA to functional protein in days
  • Case studies on challenging proteins showcasing improved expression, purification and downstream usability, accelerating structural biology and drug discovery

Learning objectives:

  • Understand the challenges of membrane protein expression and purification, and why conventional methods often fall short.
  • Explore how Cube Biotech’s portfolio of membrane stabilizing products enhance protein stability and folding.
  • Learn how the eProtein Discovery™ system enables rapid and automated cell-free expression of membrane proteins, producing functional, assay-ready results in just 48 hours.
  • Gain insights from real-world case studies from Cube Biotech and Nuclera, illustrating how this integrated approach accelerates structural and functional analysis for high-value protein targets.

Speakers:

portrait of Stephanie (Stevie) Reikine Nuclera

Stephanie Reikine PhD

Associate Director - Workflow Integration, Nuclera
Stevie is an Associate Director of Workflow Integration at Nuclera, working with teams from bio to software to deliver robust, game-changing product features that resonate with customers. With a PhD in biophysics and structural biology from Yale and a postdoc at the University of Cambridge, Stevie brings a wealth of knowledge in protein science and in biotech tools for protein research. She loves working in diverse teams and connecting ideas across different disciplines to turn R&D ideas into launched products.
Andreas Kiessling Project Manager CubeBiotech

Andreas Kiessling PhD

Project Manager, Cube Biotech
Andreas is part of the Service Team at Cube Biotech to provide custom solutions in the space of membrane protein research. He is a protein biochemist by training and obtained his PhD at the University of Leeds where he worked on the structural solution of different membrane protein classes. In his first industry position after his PhD, he obtained significant experience with cell-free systems before moving on to a more commercial position as part of Cube Biotech. Pragmatic by nature he loves to find solutions for every problem - even the ones you are not yet aware of.

About eProtein Discovery

Nuclera's eProtein Discovery™ system combines digital microfluidic droplet automation with cell-free protein synthesis technologies, it empowers protein scientists to identify the best conditions for expressing and purifying proteins of interest within 24 hours, all on a single consumable cartridge.

The system offers a significant advantage over traditional protein expression methods, allowing researchers to save time and resources by simplifying and automating the process. Its ability to handle multiple genes and customizable cell-free blends makes it a valuable tool for protein scientists in academia and the biopharma industry.