Decision-grade data to illuminate your path to protein

The streamlined eProtein Discovery™ Cloud Software allows you to easily design your DNA constructs, customize your experimental plans, carry out complex data analysis, and generate clear reports

Get the screening data you need to have the best chance of protein success from day one.

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Features and Benefits

eProtein Discovery Software simplifies a complex multivariate experimental design. The software sets up and simultaneously tracks 192 different combinations of DNA sequences, flank pairs, and expression reagent reactions for soluble proteins, and up to 88 combinations for membrane proteins.

Rigorous QA checks, supported by AI, ensure data quality and consistency of every experiment run.

The result: informative reports that your team can use to make data-driven decisions early in your protein journey.

Alphafold

AlphaFold2 inside your workflow

Visualize 3D structures and use the Variant Editor to create truncations/mutations for screening. Find out more.

Software

Plan complex screens—simply

Set up and track hundreds of construct/condition pairs with software-guided design. Reports rank pairs so teams can act.

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Data you can trust

Automated checks validate sequence compatibility and experimental setup to add confidence to decision-grade reports.

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Work anywhere

Design from your desk, monitor runs in real-time, and review results remotely.

Technical Specifications

AlphaFold2 integration Protein variant design guided by 3-D structural predictions and domain mapping.
Advanced analysis Easily interpret data from the interactive reports generated. Raw data can be exported to perform analysis with your own data analysis tools.
Remote experiment design Have the convenience to design experiments from your desk and sync with the instrument in the lab.
Experiment Progress/Email Notifications Track your experiment remotely and get alerted if action is required.
Secure single sign-on and flexible roles Single sign-on (SSO) for security and convenience. Two levels of access control (admin and project users) ensures smooth collaboration.
Connectivity modes Choose from fully cloud-connected (sync, metrics, optional remote support) or standalone with local export via LAN/NAS/USB.
Export data Exports results, videos and images to analyze experiment's data and support project progress.
Software Updates Web and instrument apps are regularly updated over-the-air with user approval.
Advanced data control and protection Manage permissions and data visibility within software. Data is protected with AES-256 encryption at rest and with TLS 1.3 in transit using a one-way API between instrument and cloud. Regular backups guarantee against data loss.

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Other Components

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Instrument

Orchestrates the multiplex protein screening workflow. Pipette and Forget™ automation minimizes hands-on time

Cartridge

Cartridge

Digital signals automate multiplex screening of constructs, tags, and conditions in parallel

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Reagents

An optimized suite of reagents for DNA preparation, protein expression screening, purifiability assessment, and off-cartridge scale-up.

Frequently Asked Questions

Yes, our web application runs on a secure cloud portal with role-based access, remote monitoring, and analysis. 

Yes. A standalone instrument is available, whereby users input their experiment directly on the instrument and locally export (LAN/NAS/USB) data.

The instrument can connect to the eProtein Discovery web application using a conventional wired internet connection, wifi network or mobile network.

As part of onboarding Nuclera will create an Admin user that can create a number of users on the platform, up to the number mentioned in the Sale Agreement.

You have complete access to all the experimental data generated on our instrument. Scientific data will be stored on the web platform. The data can be downloaded and shared in several ways. Customers can also access and share other usage information with our customer support to quickly resolve any issues.

Your data is encrypted with the AES-256 encryption standard at rest and securely transmitted to our API via TLS.

We currently have servers situated in the UK and USA.

Yes, the cloud software can be accessed throughout the world. You can design experiments, monitor the instrument and view results from anywhere.

Nuclera will provide training, online manuals & videos, and access to support scientists, to ensure users achieve the competence required to use the software and complete an experiment. Don’t worry though – we have a technical support team on hand for any issues that might arise.

PDF or CSV files containing all datapoints. MP4 videos and cartridge image shots are also part of the experiment data pack.

The instrument uses a camera to record a number of parameters. The software uses proprietary algorithms to inform the scientist on yield, purity, solubility, and purification potential of specific constructs. A number of graphs are automatically generated.

Our web and instrument applications will be automatically updated. Customers will get alerts of future updates so the process can take place without interrupting important work.

Still have questions?