ON-DEMAND WEBINAR

Genes to proteins in days: Accelerating protein expression and purification with eProtein Discovery™

Introduction:

Rapid access to high-quality proteins is essential for accelerating early discovery, screening, and proof-of-concept studies. However, traditional expression systems can be time-consuming and unpredictable. In this webinar, experts from Integrated DNA Technologies (IDT), Nuclera, and Aldevron will present a streamlined, end-to-end solution that dramatically shortens the DNA-to-protein timeline.

Sign up:

Webinar Topics:

  • How IDT’s portfolio of high-quality genes and gene fragments pair with Nuclera’s eProtein Discovery system to deliver purified, assay-ready proteins in just 48 hours.
  • A complete, automated workflow from Nuclera—from AI-guided construct design and DNA preparation to expression, purification, detection, and reporting—demonstrating how customizable cell-free expression and digital microfluidics enable rapid screening and scale-up of even the most challenging of protein targets.
  • Aldevron’s real-world case study demonstrating how their team leveraged IDT's gene fragments and Nuclera's eProtein Discovery system to rapidly screen and scale up a panel of novel chimeric fusion proteins. They generated hundreds of expression data points in weeks, and identified hits with nanomolar binding affinity, which would have taken months with traditional methods.

Learning objectives:

  • Understand how IDT’s SynBio portfolio of genes and gene fragments enables rapid and reliable protein expression.
  • Explore the complete Nuclera eProtein Discovery™ workflow, from DNA design to assay-ready protein in just 48 hours.
  • Learn how Aldevron applied this integrated solution to accelerate chimeric protein development and functional screening.

Speakers:

Photo Lucy Xu, B.S. Senior Commercial Product Manager, SynBio, Integrated DNA Technologies

Lucy Xu, B.S.

Senior Commercial Product Manager, SynBio, Integrated DNA Technologies
Lucy Xu is a product leader with over a decade of experience in biotechnology and a focus on strategic growth across the global life sciences market. At IDT, she leads product strategy for Synthetic Biology, supporting a wide range of applications including antibody discovery, protein engineering and therapeutic development. Lucy has driven multimillion dollar product growth and led global market expansion initiatives. She holds a B.S. in Bioengineering from UC San Diego.
Lawrence Welch

Lawrence Welch, PhD

Inside Sales Specialist, Nuclera
Lawrence Welch is an inside sales specialist at Nuclera, where he supports the adoption of the company’s automated, cell-free protein expression system, eProtein Discovery™. He earned his undergraduate degree in Pharmacology with industrial placement experience at the University of Manchester and completed his PhD in Sean Munro’s lab at the MRC Laboratory of Molecular Biology. Since transitioning to a commercial role in 2025, Lawrence has focused on helping researchers use cutting-edge microfluidic technology to accelerate protein discovery.
Photo Joel Francis, PhD Sr. Scientist I-Protein R&D, Aldevron

Joel Francis, PhD

Sr. Scientist I-Protein R&D, Aldevron
Joel Francis is a senior scientist in the protein R&D group at Aldevron. Joel completed his Bachelor's degree at Grand Valley State University where he majored in Cell & Molecular Biology and minored in Chemistry. He continued his training as a graduate student at Stanford University Department of Biology. His research revolved around the enzymology and functions of protein lysine methylation in gene expression regulation and cancer biology. Since joining Aldevron in 2023, his primary work revolves around the CRISPR Gene Editing product line.

This webinar was first broadcast on 26th June 2025.

About eProtein Discovery

Nuclera's eProtein Discovery™ system combines digital microfluidic droplet automation with cell-free protein synthesis technologies, it empowers protein scientists to identify the best conditions for expressing and purifying proteins of interest within 24 hours, all on a single consumable cartridge.

The system offers a significant advantage over traditional protein expression methods, allowing researchers to save time and resources by simplifying and automating the process. Its ability to handle multiple genes and customizable cell-free blends makes it a valuable tool for protein scientists in academia and the biopharma industry.