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Flyer

Flyer: Protein in-hand in 48 hours: eProtein Discovery™

In this flyer, we outline the 48-hour workflow to deliver protein in-hand including data on reproducibility, quality and quantity.

Brochure

Brochure: eProtein Discovery™ Product Specification

A comprehensive summarization of the eProtein Discovery System detailing its technical features and on which eGene kit to use for your individual needs. System specifications and ordering information is included.

Brochure

Brochure: Functional membrane proteins: Ready in 48 hours

Struggling with membrane protein expression? eProtein Discovery™ uses cell-free protein synthesis and automated additive screening to express and purify high-yield, assay-ready membrane proteins in just 48 hours. Optimize GPCR, ion channel, transporter and membrane-bound enzyme production with a streamlined workflow for cryo-EM, drug discovery, and functional assays.

Webinar

On-demand Webinar: Accelerating Drug Target Identification and Characterization

Screen, Scale, Capture, Characterize – DNA to Protein Characterization in One Week Understanding drug–target interactions is essential to improve leads, optimize pharmacokinetics and predict in vivo efficacy. The process of generating soluble, functional drug targets and studying their interactions with drugs can be complicated and time-consuming, with multiple repeats needed to optimize protein expression and…

Technical Note

Custom Additives: tailoring protein expression for your research needs Unlock the full potential of the eProtein Discovery™ system with Custom Additives

The Custom Additives manual covers how users can customize cell-free blends with additives of their own choice. This increases the flexibility for optimizing protein expression, folding and purification, by using user-chosen additives that are better tailored for their specific protein requirements while maintaining the automation and reproducibility provided by the eProtein Discovery™ system.

Application Note

Application Note: Producing active, purified human DHODH: Unlocking the power of custom additives on the eProtein Discovery™ system

This application note showcases the eProtein Discovery™ system and the Custom Additive Initiative in addressing DHODH production challenges. By supplementing Cell-free Blends with custom additives such as FMN (a DHODH cofactor, essential for activity) and Brij®-35 (a surfactant known for stabilizing complex membrane proteins), conditions were identified to produce soluble, highly purified, and enzymatically active…

Application Note

Application Note: Overcoming Discovery Challenges for Highly Disordered Transcription Factors Using eProtein Discovery™

This Application Note, covers how we employed the eProtein Discovery System to successfully express and purify full-length Transcription Factor L (TF L), along with a domain of unknown function (L2) and its binding domain (L3).

White Paper

White Paper: The value delivered by the eProtein Discovery™ workflow

This white paper investigates the cost of protein expression and the value delivered by the eProtein Discovery™ workflow. Traditionally, finding suitable conditions to obtain soluble and purifiable recombinant proteins is difficult and time-consuming. Constrained by cost, labor and throughput, typically only a few protein expression conditions are explored, with hit-and-miss results and often requiring multiple…

Application Note

Application Note: Guiding In Vivo Protein Expression with eProtein Discovery™ CFPS for Disulfide-Rich Proteins

The eProtein Discovery System simplifies the transition from cell-free protein synthesis (CFPS) to in vivo. E. coli expression, especially for intricate proteins with disulfide bonds. By evaluating numerous protein variants and up to seven solubility tags, researchers can efficiently identify optimal construct designs.

Poster

Poster: Screen, Scale, Capture, Characterize: Rapid protein production and characterization of drug-target interactions

This poster illustrates how researchers can rapidly progress from DNA to an expressed, purified, and characterized protein—demonstrated here with Bruton’s tyrosine kinase (BTK)—using the eProtein Discovery and Biacore SPR systems.

Pages: 1234

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