Resource Library

Find supporting resources for our platform.

Filter by

Resource Type

Application Note
Brochure
Flyer
Poster
Primary Literature
Technical Note
Video
Webinar
White Paper

Open Filter

Webinar

Webinar: Genes to proteins in days: Accelerating protein expression and purification with eProtein Discovery™

Join experts from IDT, Nuclera, and Aldevron for a webinar showcasing a fully integrated solution that takes you from gene to assay-ready protein in just days — not weeks.

Video

Video: Accelerating Protein Engineering with AlphaFold integrated into eProtein Discovery™

This video showcases the seamless integration of AlphaFold into Nuclera’s eProtein Discovery™ Cloud software, enabling a powerful, structure-guided approach to protein engineering.

Poster

Poster: Increasing Soluble Protein Yield: Utilizing AlphaFold for Guided Protein Variant Design And Screening

This study integrates AlphaFold’s AI-based structure prediction with high-throughput screening on the eProtein Discovery™ system to optimize protein solubility. By designing protein variants based on AlphaFold predictions and screening their expression and purification, we significantly increase soluble protein yields. Case studies on MMP-1 and MDM2 demonstrate this workflow’s efficiency, accelerating protein production for structural biology and drug discovery applications within 48 hours.

Webinar

On-demand Webinar: Rapidly Express Optimized Membrane Proteins in 48 hours

This webinar introduces the latest update to eProtein Discovery™, allowing researchers to customize cell-free expression conditions to improve yields of co-factor dependent membrane proteins.

WEBINAR Rapidly Express Optimized Membrane Proteins in 48 hours Speaker: Toby Ost (SVP Product Development)

Brochure

Brochure: eProtein Discovery™ Product Specification

A comprehensive summarization of the eProtein Discovery System detailing its technical features and on which eGene kit to use for your individual needs. System specifications and ordering information is included.

Webinar

On-demand Webinar: Accelerating Drug Target Identification and Characterization

Screen, Scale, Capture, Characterize – DNA to Protein Characterization in One Week Understanding drug–target interactions is essential to improve leads, optimize pharmacokinetics and predict in vivo efficacy. The process of generating soluble, functional drug targets and studying their interactions with drugs can be complicated and time-consuming, with multiple repeats needed to optimize protein expression and…

Technical Note

Custom Additives: tailoring protein expression for your research needs Unlock the full potential of the eProtein Discovery™ system with Custom Additives

The Custom Additives manual covers how users can customize cell-free blends with additives of their own choice. This increases the flexibility for optimizing protein expression, folding and purification, by using user-chosen additives that are better tailored for their specific protein requirements while maintaining the automation and reproducibility provided by the eProtein Discovery™ system.

White Paper

White Paper: The value delivered by the eProtein Discovery™ workflow

This white paper investigates the cost of protein expression and the value delivered by the eProtein Discovery™ workflow. Traditionally, finding suitable conditions to obtain soluble and purifiable recombinant proteins is difficult and time-consuming. Constrained by cost, labor and throughput, typically only a few protein expression conditions are explored, with hit-and-miss results and often requiring multiple…

Application Note

Application Note: Guiding In Vivo Protein Expression with eProtein Discovery™ CFPS for Disulfide-Rich Proteins

The eProtein Discovery System simplifies the transition from cell-free protein synthesis (CFPS) to in vivo. E. coli expression, especially for intricate proteins with disulfide bonds. By evaluating numerous protein variants and up to seven solubility tags, researchers can efficiently identify optimal construct designs.

Webinar

On-demand Webinar: Defying Difficult-to-Express Proteins – Overcoming Protein Expression Challenges

In this webinar, we will explore how the eProtein Discovery™ System addresses the challenges of expressing difficult-to-express proteins, such as transcription factors, proteins with disordered regions and disulfide bonds. Leveraging advanced cell-free protein synthesis (CFPS) and digital microfluidic technology, this system enables researchers to rapidly produce soluble, purified proteins within 48 hours.

Pages: 12345

eProtein Discovery System

Automated multiplex protein screening system

Instrument

Cartridge

Reagents

Software