New: Nuclera Expands eProtein Discovery™ with New Membrane Protein Workflow - Read Now

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Webinar

On-demand Webinar: Intro to Rapid Protein Expression Automation with eProtein Discovery

The eProtein Discovery™ System can screen multiple protein expression and purification profiles and deliver reliable proteins in-hand in less than 48 hours. Revolutionizing laboratory workflows and making a demonstrable impact in terms of time to publish in academia and drug discovery timelines.

On-demand webinar Automated Protein Expression Series Intro to Rapid Protein Expression Automation with eProtein Discovery™

Poster

Poster: DNA to assay-ready proteins in 48 hours. Rapid protein expression and purification on the eProtein Discovery™ system and binding confirmation on Biacore™ SPR System

We show in this poster evidence from combining rapid protein obtainability on the eProtein Discovery™ system, and functional activity via protein-protein interaction studies on Biacore™ SPR system. This workflow is demonstrated using a difficult-to-express protein VEGF165, known to contain disulfide bonds.

Nuclera Poster VEGF165 Binding Confirmation Mockup Image

Webinar

On-demand Webinar: Overcoming the Inexpressible: How cell-free protein synthesis solved the E. coli toxicity hurdle

Overcoming the Inexpressible: How cell-free protein synthesis solved the E. coli toxicity hurdle. Learn how the eProtein Discovery™ enabled optimization of the expression conditions for an GCN5-Related N-Acetyltransferase protein and gain insights into its antibiotic resistance mechanism.

Brochure

eProtein Discovery™ construct design and expression optimization guide

This brochure covers how you can simultaneously screen 24 DNA constructs across 8 customizable Cell-free Blends, ensuring optimal protein yield and delivering results in just 48 hours. Explore how eProtein Discovery revolutionizes protein production with unparalleled speed and success.

Application Note

Application Note: Screening the effects of solubility tags and their removal (detagging) with 3C protease on cell-free protein expression using the eProtein Discovery™ System

The ability to evaluate the effect of different solubility tags on protein expression and the impact of their removal can be done simultaneously on eProtein Discovery. Data in this application note validates the benefit of having a solubility tag during expression and confirming that removal of the solubility tag retains yield.